Title : Caenorhabditis elegans S-adenosylmethionine decarboxylase is highly stimulated by putrescine but exhibits a low specificity for activator binding.

Pub. Date : 2003 Jan

PMID : 12674502






2 Functional Relationships(s)
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Protein Name
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1 Putrescine, a well-known stimulator of mammalian AdoMetDC activity, enhances the catalytic activity of the nematode enzyme 350-fold. Putrescine adenosylmethionine decarboxylase 1 Homo sapiens
2 Although C. elegans AdoMetDC exhibits a low specificity toward activator molecules, the amino acid residues that were shown to be involved in putrescine binding of the human enzyme are conserved in the nematode enzyme. Putrescine adenosylmethionine decarboxylase 1 Homo sapiens