Title : Differential regulation of HIF-1 alpha prolyl-4-hydroxylase genes by hypoxia in human cardiovascular cells.

Pub. Date : 2003 Apr 11

PMID : 12670503






1 Functional Relationships(s)
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Protein Name
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1 Three HIF-alpha prolyl-4-hydroxylases (PHDs) (named PHD1, PHD2, and PHD3) effect the proteasome-mediated degradation of HIF by catalyzing the hydroxylation of key proline residues in the HIF-1 alpha subunit under normoxic conditions. Proline hypoxia inducible factor 1 subunit alpha Homo sapiens