Title : CCAAT/enhancer-binding protein and activator protein-1 transcription factors regulate the expression of interleukin-8 through the mitogen-activated protein kinase pathways in response to mechanical stretch of human airway smooth muscle cells.

Pub. Date : 2003 May 23

PMID : 12637525






1 Functional Relationships(s)
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1 Our data demonstrate that the cyclic stretch of HASMC causes the increased production of IL-8 by activating the AP-1 and C/EBP transcription factors through the activation of ERK1/2 and p38 kinase signaling pathways. hasmc C-X-C motif chemokine ligand 8 Homo sapiens