Title : Nicotinic acetylcholine receptor subunits and receptor activity in the epithelial cell line HT29.

Pub. Date : 2003 Mar 28

PMID : 12628462






2 Functional Relationships(s)
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1 IL-8 release was measured by ELISA from cells activated for 6 h with TNFalpha (50 ng ml(-1)) in the absence and presence of nicotine (10(-11)-10(-6) M). Nicotine C-X-C motif chemokine ligand 8 Homo sapiens
2 Nicotine significantly inhibited TNFalpha-induced IL-8 release in a concentration related manner with peak inhibition occurring at 10(-7) M (2.39 +/- 0.78 ng ml(-1), n = 5). Nicotine C-X-C motif chemokine ligand 8 Homo sapiens