Title : Conditional expression of murine Flt3 ligand leads to expansion of multiple dendritic cell subsets in peripheral blood and tissues of transgenic mice.

Pub. Date : 2003 Mar 15

PMID : 12626534






3 Functional Relationships(s)
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1 We used the tetracycline-inducible system to conditionally express murine Flt3 ligand (FL), a potent hemopoietic growth factor that promotes the differentiation and mobilization of DC. Tetracycline FMS-like tyrosine kinase 3 ligand Mus musculus
2 We used the tetracycline-inducible system to conditionally express murine Flt3 ligand (FL), a potent hemopoietic growth factor that promotes the differentiation and mobilization of DC. Tetracycline FMS-like tyrosine kinase 3 ligand Mus musculus
3 Acute treatment (96 h) of the transgenic animals with the tetracycline analog doxycycline (DOX) promoted an approximately 200-fold increase in serum levels of FL without affecting the number of circulating DC. Tetracycline FMS-like tyrosine kinase 3 ligand Mus musculus