Pub. Date : 2003 Jul 1
PMID : 12623841
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Furthermore, TPO-stimulated cellular proliferation appears to be directly correlated with receptor internalization, indicating that internalization of the TPO/Mpl complex may be essential for normal signal transduction. | (2,4,6-trimethylbenzoyl) diphenylphosphine oxide | MPL proto-oncogene, thrombopoietin receptor | Homo sapiens |
| 2 | Finally, we have demonstrated that upon removal of TPO from the supernatant, Mpl promptly reappears on the cell surface, suggesting that a pool of intracellular Mpl can be rapidly recycled to the cell surface. | (2,4,6-trimethylbenzoyl) diphenylphosphine oxide | MPL proto-oncogene, thrombopoietin receptor | Homo sapiens |
| 3 | Finally, we have demonstrated that upon removal of TPO from the supernatant, Mpl promptly reappears on the cell surface, suggesting that a pool of intracellular Mpl can be rapidly recycled to the cell surface. | (2,4,6-trimethylbenzoyl) diphenylphosphine oxide | MPL proto-oncogene, thrombopoietin receptor | Homo sapiens |
| 4 | These data help identify the receptor motifs involved in TPO-induced internalization of Mpl and suggest that Mpl translocation may be necessary for normal cellular proliferation. | (2,4,6-trimethylbenzoyl) diphenylphosphine oxide | MPL proto-oncogene, thrombopoietin receptor | Homo sapiens |
| 5 | These data help identify the receptor motifs involved in TPO-induced internalization of Mpl and suggest that Mpl translocation may be necessary for normal cellular proliferation. | (2,4,6-trimethylbenzoyl) diphenylphosphine oxide | MPL proto-oncogene, thrombopoietin receptor | Homo sapiens |