Title : Glucose-6-phosphate dehydrogenase overexpression decreases endothelial cell oxidant stress and increases bioavailable nitric oxide.

Pub. Date : 2003 Mar 1

PMID : 12615686






3 Functional Relationships(s)
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Protein Name
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1 OBJECTIVE: Glucose-6-phosphate dehydrogenase (G6PD), the principal source of NADPH, serves as an antioxidant enzyme to modulate the redox milieu and nitric oxide synthase activity. NADP glucose-6-phosphate dehydrogenase Bos taurus
2 OBJECTIVE: Glucose-6-phosphate dehydrogenase (G6PD), the principal source of NADPH, serves as an antioxidant enzyme to modulate the redox milieu and nitric oxide synthase activity. NADP glucose-6-phosphate dehydrogenase Bos taurus
3 METHODS AND RESULTS: Adenoviral-mediated gene transfer of G6PD increased G6PD expression, activity, and NADPH levels in bovine aortic endothelial cells (BAECs). NADP glucose-6-phosphate dehydrogenase Bos taurus