Title : Combined RAR alpha- and RXR-specific ligands overcome N-myc-associated retinoid resistance in neuroblastoma cells.

Pub. Date : 2003 Mar 14

PMID : 12615055






1 Functional Relationships(s)
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1 Combination of receptor-specific retinoid agonists for RXR and RAR alpha significantly enhanced the sensitivity of N-myc-amplified neuroblastoma cells to the growth inhibitory effects of aRA. Tretinoin MYCN proto-oncogene, bHLH transcription factor Homo sapiens