Title : Examination of the differences in structure-function of human and rat 3alpha-hydroxysteroid dehydrogenase.

Pub. Date : 2003 Feb 1

PMID : 12604225






2 Functional Relationships(s)
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1 Comparison of the crystal structure of AKR1C2-NADP(+)-ursodeoxycholate ternary complex (3.0 A) with that of the AKR1C9-NADP(+)-testosterone ternary complex (2.8 A) demonstrates the expected conservancy in overall structure and active site topology. NADP aldo-keto reductase family 1 member C2 Homo sapiens
2 Comparison of the crystal structure of AKR1C2-NADP(+)-ursodeoxycholate ternary complex (3.0 A) with that of the AKR1C9-NADP(+)-testosterone ternary complex (2.8 A) demonstrates the expected conservancy in overall structure and active site topology. NADP aldo-keto reductase family 1 member C2 Homo sapiens