Title : Up-regulation of aldose reductase by the substrate, methylglyoxal.

Pub. Date : 2003 Feb 1

PMID : 12604218






1 Functional Relationships(s)
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1 Under oxidative stress generated by hydrogen peroxide, the major signaling pathway mediating the up-regulation of AR expression was demonstrated to be the epidermal growth factor receptor-ERK pathway. Hydrogen Peroxide epidermal growth factor receptor Homo sapiens