Title : Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's disease.

Pub. Date : 2003 Mar

PMID : 12603833






1 Functional Relationships(s)
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1 In summary, our data indicate a major role for VR1 receptors, as compared to CB1 receptors, in the antihyperkinetic effects and the recovery of neurochemical deficits caused in 3NP-lesioned rats by compounds that activate both CB1 and VR1 receptors, either directly or via manipulation of the levels of endogenous agonists. 3-nitropropionic acid transient receptor potential cation channel, subfamily V, member 1 Rattus norvegicus