Pub. Date : 2003 Feb 25
PMID : 12600906
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Activation of PAR-2 receptors in vivo dilated human blood vessels in a dose-dependent manner, and the effects were reduced by inhibition of both nitric oxide and prostanoid synthesis CONCLUSIONS: These findings demonstrate that serine protease activity can cause human vasodilation and provide a possible explanation of why serine protease activation in critical illness is associated with vascular dysfunction. | Prostaglandins | coagulation factor II, thrombin | Homo sapiens |