Title : Effects of steroid hormones on calcitonin gene-related peptide receptors in cultured human myometrium.

Pub. Date : 2003 Feb

PMID : 12592257






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1 CONCLUSION: We conclude from this study that (1) the messenger RNA expression of estrogen receptor-alpha and progesterone receptor in pregnant myometrium were maintained at relatively high levels (>89%) within 48 hours incubation and that this may be useful for in vitro studies that are designed to evaluate the effects of sex steroids on the human myometrium during pregnancy and that (2) estrogen inhibits and progesterone stimulates the expression of calcitonin gene-related peptide B receptors in cultured pregnant myometrial explants. Steroids estrogen receptor 1 Homo sapiens