Title : ACE-versus chymase-dependent angiotensin II generation in human coronary arteries: a matter of efficiency?

Pub. Date : 2003 Feb 1

PMID : 12588767






1 Functional Relationships(s)
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1 Separate inhibition of ACE (with captopril) and chymase (with C41 or chymostatin) shifted the angiotensin I concentration-response curve approximately 5-fold to the right, whereas a 10-fold shift occurred during combined ACE and chymase inhibition. Captopril angiotensinogen Homo sapiens