Title : Regulation of uncoupling protein-2 mRNA in L6 myotubules: I: Thiazolidinediones stimulate uncoupling protein-2 gene expression by a mechanism requiring ongoing protein synthesis and an active mitogen-activated protein kinase.

Pub. Date : 2002 Nov

PMID : 12588051






1 Functional Relationships(s)
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Protein Name
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1 Blockade of protein synthesis with cycloheximide as well as abrogation of mitogen-activated protein kinase (MAPK) activity with PD98059 or U0126 also prevented the TZD-induced increase in UCP2 mRNA. Cycloheximide uncoupling protein 2 Homo sapiens