Title : Green tea polyphenol epigallocatechin-3 gallate induces apoptosis of proliferating vascular smooth muscle cells via activation of p53.

Pub. Date : 2003 Apr

PMID : 12586742






2 Functional Relationships(s)
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1 Treatment with 80 microg/ml EGCG induced the tumor suppressor p53, which was functional as judged by activation of the target cyclin-dependent kinase inhibitor p21CIP1. epigallocatechin gallate tumor protein p53 Homo sapiens
2 Thus, EGCG inhibits growth and induces death of SMCs in a p53- and NF-kappaB-dependent manner. epigallocatechin gallate tumor protein p53 Homo sapiens