Title : Haem oxygenase 1 gene induction by glucose deprivation is mediated by reactive oxygen species via the mitochondrial electron-transport chain.

Pub. Date : 2003 May 1

PMID : 12585963






1 Functional Relationships(s)
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1 Either N-acetylcysteine, an antioxidant, or deferoxamine, an iron chelator, resulted in a dose-dependent inhibition of HO-1 mRNA and protein induction during glucose deprivation, suggesting a redox- and iron-dependent mechanism. Deferoxamine heme oxygenase 1 Homo sapiens