Title : Metabolism of chloroform in the human liver and identification of the competent P450s.

Pub. Date : 2003 Mar

PMID : 12584152






2 Functional Relationships(s)
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1 The high affinity process was catalyzed by CYP2E1, as clearly indicated by kinetic studies, correlation with chlorzoxazone 6-hydroxylation (r = 0.837; p < 0.001), and inhibition by monoclonal antihuman CYP2E1 and 4-methylpyrazole. Fomepizole cytochrome P450 family 2 subfamily E member 1 Homo sapiens
2 The high affinity process was catalyzed by CYP2E1, as clearly indicated by kinetic studies, correlation with chlorzoxazone 6-hydroxylation (r = 0.837; p < 0.001), and inhibition by monoclonal antihuman CYP2E1 and 4-methylpyrazole. Fomepizole cytochrome P450 family 2 subfamily E member 1 Homo sapiens