Pub. Date : 2003 Mar
PMID : 12583828
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Methotrexate inhibits dihydrofolate reductase, which leads to accumulation of polyglutamated folates, causing further inhibition of thymidylate synthase and glycinamide ribonucleotide formyltransferase. | Folic Acid | dihydrofolate reductase | Homo sapiens |