Pub. Date : 2003 Feb
PMID : 12580960
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Overexpression of manganese superoxide dismutase promotes survival in cell lines after doxorubicin treatment. | Doxorubicin | superoxide dismutase 2 | Homo sapiens |
| 2 | The present study was performed to determine whether over-expression of MnSOD may play a role in resistance to doxorubicin. | Doxorubicin | superoxide dismutase 2 | Homo sapiens |
| 3 | In contrast, A375 and U937 cells transduced with the MNSOD gene consistently demonstrate increased colony formation in the presence of increasing concentrations of doxorubicin. | Doxorubicin | superoxide dismutase 2 | Homo sapiens |
| 4 | These results indicate that overexpression of MnSOD can enhance resistance to doxorubicin treatment. | Doxorubicin | superoxide dismutase 2 | Homo sapiens |