Title : Increased 99mTc-sestamibi accumulation in normal liver and drug-resistant tumors after the administration of the glycoprotein inhibitor, XR9576.

Pub. Date : 2003 Feb

PMID : 12576431






6 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 99mTc-sestamibi, a substrate of the multidrug transporter P-glycoprotein (Pgp), has been used as a functional imaging agent for the multidrug resistance-1 (MDR1) phenotype. Technetium Tc 99m Sestamibi ATP binding cassette subfamily B member 1 Homo sapiens
2 99mTc-sestamibi, a substrate of the multidrug transporter P-glycoprotein (Pgp), has been used as a functional imaging agent for the multidrug resistance-1 (MDR1) phenotype. Technetium Tc 99m Sestamibi ATP binding cassette subfamily B member 1 Homo sapiens
3 99mTc-sestamibi, a substrate of the multidrug transporter P-glycoprotein (Pgp), has been used as a functional imaging agent for the multidrug resistance-1 (MDR1) phenotype. Technetium Tc 99m Sestamibi ATP binding cassette subfamily B member 1 Homo sapiens
4 99mTc-sestamibi, a substrate of the multidrug transporter P-glycoprotein (Pgp), has been used as a functional imaging agent for the multidrug resistance-1 (MDR1) phenotype. Technetium Tc 99m Sestamibi ATP binding cassette subfamily B member 1 Homo sapiens
5 In vitro, retention of (99m)Tc-sestamibi by cells that overexpress Pgp can be enhanced by the addition of Pgp inhibitors. Technetium Tc 99m Sestamibi ATP binding cassette subfamily B member 1 Homo sapiens
6 In vitro, retention of (99m)Tc-sestamibi by cells that overexpress Pgp can be enhanced by the addition of Pgp inhibitors. Technetium Tc 99m Sestamibi ATP binding cassette subfamily B member 1 Homo sapiens