Title : Local insulin-like growth factor-II mediates prolactin-induced mammary gland development.

Pub. Date : 2003 Mar

PMID : 12554791






1 Functional Relationships(s)
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1 Finally, induction of insulin receptor substrate (IRS)-1 in the mammary glands of PRL-treated mice and induction of IRS-1 and IRS-2 after treatment with PRL plus progesterone indicates that these molecules are induced by PRL as potential signaling intermediates downstream from IGF-I/insulin receptors. Progesterone insulin-like growth factor 1 Mus musculus