Title : 22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion.

Pub. Date : 2003 Apr 11

PMID : 12547833






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In non-neuronal and neuronal cells overexpressing a human Swedish variant of amyloid precursor protein, 22R-hydroxycholesterol and 9-cis-retinoic acid induced ABCA1 expression and increased apoA-I-mediated cholesterol efflux consequently decreasing cellular cholesterol content. Alitretinoin apolipoprotein A1 Homo sapiens