Pub. Date : 1975 Jun 30
PMID : 125463
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Specific binding of tranexamic acid to plasmin. | Tranexamic Acid | plasminogen | Homo sapiens |
| 2 | On the other hand, tranexamic acid bound to human plasmin with a dissociation constant of 3.5 X 10-5 M, which was very close to the inhibition constatn (3.6 X 10-5 M1 for this compound in inhibiting plasmin-induced fibrinolysis. | Tranexamic Acid | plasminogen | Homo sapiens |
| 3 | On the other hand, tranexamic acid bound to human plasmin with a dissociation constant of 3.5 X 10-5 M, which was very close to the inhibition constatn (3.6 X 10-5 M1 for this compound in inhibiting plasmin-induced fibrinolysis. | Tranexamic Acid | plasminogen | Homo sapiens |
| 4 | The binding site of tranexamic acid on plasmin was not the catalytic site of plasmin, because TLCK-blocked plasmin also showed a similar affinity to tranexamic acid (the dissociation constant, 2.9-4.8 x 10-5m). | Tranexamic Acid | plasminogen | Homo sapiens |
| 5 | The binding site of tranexamic acid on plasmin was not the catalytic site of plasmin, because TLCK-blocked plasmin also showed a similar affinity to tranexamic acid (the dissociation constant, 2.9-4.8 x 10-5m). | Tranexamic Acid | plasminogen | Homo sapiens |
| 6 | in the binding studies with the highly purified plasminogen and TLCK-plasmin preparations which were obtained by affinity chromatography on lysine-substituted Sepharose, the molar binding ratio was shown to be 1.5-1.6 moles tranexamic acid per one mole protein. | Tranexamic Acid | plasminogen | Homo sapiens |