Pub. Date : 2003 Feb
PMID : 12542697
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | New insights into the P-glycoprotein-mediated effluxes of rhodamines. | Rhodamines | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | The kinetic parameter, ka = VM/km, which is a measure of the efficiency of the P-gp-mediated efflux of a substrate was similar for almost all the rhodamine analogues tested. | Rhodamines | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | Our conclusion is that the compounds of these two classes of molecules, anthracyclines and rhodamines, are substrates of P-gp and that their pumping rates at limiting low substrate concentration are similar. | Rhodamines | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | The findings presented here are the first to show quantitative information about the kinetic parameters for P-gp-mediated efflux of rhodamine analogues in intact cells. | Rhodamines | ATP binding cassette subfamily B member 1 | Homo sapiens |