Title : Fusion of the CH1 domain of IgG1 to epidermal growth factor (EGF) prolongs its retention in the blood but does not increase tumor uptake.

Pub. Date : 2002 Dec

PMID : 12537670






1 Functional Relationships(s)
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1 Expression vector pGEX2T was transfected into E. coli (BL-21) and hEGF-CH1 expressed by induction of the lac Iq promotor with 50 microM isopropyl beta-D-thiogalactopyranoside (IPTG). Isopropyl Thiogalactoside epidermal growth factor Homo sapiens