Title : Spin trapping of superoxide in the presence of beta-cyclodextrins.

Pub. Date : 2002 Dec 21

PMID : 12536801






2 Functional Relationships(s)
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1 The trapping of superoxide anion with DMPO and DEPMPO has been carried out in the presence of a methylated beta-cyclodextrin, Me-beta-CD; inclusion of the spin adducts in the cavity of Me-beta-CD resulted in a seven-fold increase of their half-life (t1/2 = 96 min for DEPMPO-superoxide spin adduct) and in their protection towards glutathione peroxidase (Gpx) and also ascrobate anion in the case of DEPMPO. 5,5-dimethyl-1-pyrroline-1-oxide spindlin 1 Homo sapiens
2 The trapping of superoxide anion with DMPO and DEPMPO has been carried out in the presence of a methylated beta-cyclodextrin, Me-beta-CD; inclusion of the spin adducts in the cavity of Me-beta-CD resulted in a seven-fold increase of their half-life (t1/2 = 96 min for DEPMPO-superoxide spin adduct) and in their protection towards glutathione peroxidase (Gpx) and also ascrobate anion in the case of DEPMPO. 5,5-dimethyl-1-pyrroline-1-oxide spindlin 1 Homo sapiens