Title : Prior aspirin use in unstable angina patients with modified plasma inflammatory markers and endothelial nitric oxide synthase in neutrophils.

Pub. Date : 2002 Dec

PMID : 12534448






6 Functional Relationships(s)
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Compound Name
Protein Name
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1 Prior aspirin use in unstable angina patients with modified plasma inflammatory markers and endothelial nitric oxide synthase in neutrophils. Aspirin nitric oxide synthase 3 Homo sapiens
2 The aim of this study was to explore if prior aspirin therapy in unstable angina (UA) patients could modify systemic inflammatory markers such as interleukin-6 (IL-6), tumour necrosis factor-alpha (TNF-alpha) and intercellular adhesion molecule-1 (ICAM-1) and the expression of endothelial nitric oxide synthase (eNOS) in neutrophils. Aspirin nitric oxide synthase 3 Homo sapiens
3 The aim of this study was to explore if prior aspirin therapy in unstable angina (UA) patients could modify systemic inflammatory markers such as interleukin-6 (IL-6), tumour necrosis factor-alpha (TNF-alpha) and intercellular adhesion molecule-1 (ICAM-1) and the expression of endothelial nitric oxide synthase (eNOS) in neutrophils. Aspirin nitric oxide synthase 3 Homo sapiens
4 The eNOS protein expression was also higher in neutrophils from the UA patients taking aspirin than in those not taking aspirin. Aspirin nitric oxide synthase 3 Homo sapiens
5 The eNOS protein expression was also higher in neutrophils from the UA patients taking aspirin than in those not taking aspirin. Aspirin nitric oxide synthase 3 Homo sapiens
6 CONCLUSION: Patients taking aspirin before UA showed a lower systemic inflammatory response and higher eNOS protein expression in their neutrophils Aspirin nitric oxide synthase 3 Homo sapiens