Title : Expression of endothelin 1 in rat random-pattern skin flaps treated with topical nifedipine.

Pub. Date : 2003 Jan-Feb

PMID : 12533145






3 Functional Relationships(s)
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1 Expression of endothelin 1 in rat random-pattern skin flaps treated with topical nifedipine. Nifedipine endothelin 1 Rattus norvegicus
2 RESULTS: The ET-1 levels in the distal (necrotic) flap segments were increased by 4.53 pg/mL over baseline (nonnecrotic) flaps in the placebo-treated animals and decreased by 4.70 pg/mL below baseline in the nifedipine-treated group (P =.03). Nifedipine endothelin 1 Rattus norvegicus
3 Moreover, treatment with topical nifedipine may antagonize the vasoconstrictive effects of ET-1. Nifedipine endothelin 1 Rattus norvegicus