Pub. Date : 2003 Feb 15
PMID : 12532330
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Raf-independent and MEKK1-dependent activation of NF-kappaB by hydrogen peroxide in 70Z/3 pre-B lymphocyte tumor cells. | Hydrogen Peroxide | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 2 | Especially, MEK1 may contribute to H(2)O(2)-induced NF-kappaB activation as shown in the inhibition of NF-kappaB binding activity by the MEK1 inhibitor, PD 98059, and H(2)O(2)-induced MEK1 activation. | Hydrogen Peroxide | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 3 | Especially, MEK1 may contribute to H(2)O(2)-induced NF-kappaB activation as shown in the inhibition of NF-kappaB binding activity by the MEK1 inhibitor, PD 98059, and H(2)O(2)-induced MEK1 activation. | Hydrogen Peroxide | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 4 | Especially, MEK1 may contribute to H(2)O(2)-induced NF-kappaB activation as shown in the inhibition of NF-kappaB binding activity by the MEK1 inhibitor, PD 98059, and H(2)O(2)-induced MEK1 activation. | Hydrogen Peroxide | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 5 | Especially, MEK1 may contribute to H(2)O(2)-induced NF-kappaB activation as shown in the inhibition of NF-kappaB binding activity by the MEK1 inhibitor, PD 98059, and H(2)O(2)-induced MEK1 activation. | Hydrogen Peroxide | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 6 | Therefore, our data suggest that H(2)O(2) regulates the activity of NF-kappaB by MEK1 activation through MEKK1-dependent but Ras/Raf-independent mechanism. | Hydrogen Peroxide | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |