Title : Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents.

Pub. Date : 2003 May 15

PMID : 12531810






1 Functional Relationships(s)
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1 2-Methoxyestradiol (2-ME), a new anticancer agent currently in clinical trials, has been demonstrated to inhibit superoxide dismutase (SOD) and to induce apoptosis in leukemia cells through a free radical-mediated mechanism. Free Radicals superoxide dismutase 1 Homo sapiens