Title : cAMP elevators inhibit LPS-induced IL-12 p40 expression by interfering with phosphorylation of p38 MAPK in murine peritoneal macrophages.

Pub. Date : 2002 Dec

PMID : 12528891






1 Functional Relationships(s)
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1 We previously found that the cAMP-elevators (CTx and 8-Br-cAMP) inhibited IL-12, IL-la, IL-6 gene expression, but increased the transcriptional levels of IL-10 and IL-1Ra in LPS-treated murine peritoneal macrophages. 8-Bromo Cyclic Adenosine Monophosphate interleukin 6 Mus musculus