Title : Cell type-dependent activation of 5-lipoxygenase by arachidonic acid.

Pub. Date : 2003 Jan

PMID : 12525578






1 Functional Relationships(s)
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1 We show that stimulation of polymorphonuclear leukocytes (PMNL), rat basophilic leukemia (RBL)-1, or transfected HeLa cells with arachidonic acid (AA) caused prominent 5-LO product formation that coincided with the activity of extracellular signal-regulated kinases (ERKs) and p38 mitogen-activated protein kinase. Arachidonic Acid mitogen-activated protein kinase 14 Homo sapiens