Pub. Date : 2003 Jan
PMID : 12525568
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Cerivastatin and atorvastatin inhibit IL-3-dependent differentiation and IgE-mediated histamine release in human basophils and downmodulate expression of the basophil-activation antigen CD203c/E-NPP3. | Histamine | immunoglobulin heavy constant epsilon | Homo sapiens |
2 | Preincubation of blood basophils with cerivastatin or atorvastatin (0.1-100 microM) for 24 h reduced their capacity to release histamine on immunoglobulin E (IgE)-dependent stimulation in a dose-dependent manner. | Histamine | immunoglobulin heavy constant epsilon | Homo sapiens |
3 | Preincubation of blood basophils with cerivastatin or atorvastatin (0.1-100 microM) for 24 h reduced their capacity to release histamine on immunoglobulin E (IgE)-dependent stimulation in a dose-dependent manner. | Histamine | immunoglobulin heavy constant epsilon | Homo sapiens |