Title : Improved biological activity of Gly2- and Ser2-substituted analogues of glucose-dependent insulinotrophic polypeptide.

Pub. Date : 2003 Jan

PMID : 12525257






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These data indicate that substitution of the penultimate Ala2 in GIP by Gly or Ser confers resistance to plasma DPP IV degradation, resulting in enhanced biological activity, therefore raising the possibility of their use in the treatment of type 2 diabetes. Serine dipeptidyl peptidase 4 Homo sapiens