Title : Experimental therapy of human prostate cancer by inhibiting MDM2 expression with novel mixed-backbone antisense oligonucleotides: in vitro and in vivo activities and mechanisms.

Pub. Date : 2003 Feb 15

PMID : 12518324






1 Functional Relationships(s)
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1 The antisense oligonucleotide also potentiated the effects of p53 activation and p21 induction by chemotherapeutic agents 10-hydroxycamptothecin, adriamycin, 5-fluorouracil, and paclitaxel. Paclitaxel tumor protein p53 Homo sapiens