Title : Reactive oxygen species upregulate expression of PAI-1 in endothelial cells.

Pub. Date : 2002

PMID : 12511973






1 Functional Relationships(s)
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1 Upregulation of PAI-1 expression in endothelial cells by the stimulation with TNFalpha (50 ng/ml) or H2O2 (10-200 micro M), observed by measurement of the antigen and mRNA levels, was reversed in the presence of NAC (20mM). Hydrogen Peroxide serpin family E member 1 Homo sapiens