Title : TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions.

Pub. Date : 2003 Jan

PMID : 12508053






2 Functional Relationships(s)
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1 Fura-2 quenching experiments with Mn(2+), Co(2+), or Ni(2+) suggest that these can be transported by TRPM7 in the presence of physiological levels of Ca(2+) and Mg(2+), suggesting that TRPM7 represents a novel ion-channel mechanism for cellular metal ion entry into vertebrate cells. Fura-2 transient receptor potential cation channel subfamily M member 7 Homo sapiens
2 Fura-2 quenching experiments with Mn(2+), Co(2+), or Ni(2+) suggest that these can be transported by TRPM7 in the presence of physiological levels of Ca(2+) and Mg(2+), suggesting that TRPM7 represents a novel ion-channel mechanism for cellular metal ion entry into vertebrate cells. Fura-2 transient receptor potential cation channel subfamily M member 7 Homo sapiens