Title : Oxidized-LDL through LOX-1 increases the expression of angiotensin converting enzyme in human coronary artery endothelial cells.

Pub. Date : 2003 Jan

PMID : 12504834






2 Functional Relationships(s)
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Protein Name
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1 Simvastatin markedly attenuated ox-LDL-induced MAPK activation, and concurrently reduced ACE expression (P<0.01 vs. ox-LDL alone). Simvastatin angiotensin I converting enzyme Homo sapiens
2 Simvastatin, which inhibits MAPK activation, also blocks ox-LDL-mediated upregulation of ACE. Simvastatin angiotensin I converting enzyme Homo sapiens