Title : [Relationship between cyclooxygenase-2 protein expression, prostaglandins levels and biologic behavior in ovarian carcinoma tissue].

Pub. Date : 2002 Nov

PMID : 12487927






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 (3) COX-2 expression was correlated with PGE(2), 6-keto-PGF(1 alpha) and TXB(2) (P < 0.01). Prostaglandins E mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 CONCLUSIONS: (1) Our data suggest that COX-2 overexpression leads to increased PGE(2), 6-keto-PGF(1 alpha) and TXB(2) biosynthesis, which may be mechanisms underlying the contribution of COX-2 to the development of ovarian serous carcinoma. Prostaglandins E mitochondrially encoded cytochrome c oxidase II Homo sapiens
3 CONCLUSIONS: (1) Our data suggest that COX-2 overexpression leads to increased PGE(2), 6-keto-PGF(1 alpha) and TXB(2) biosynthesis, which may be mechanisms underlying the contribution of COX-2 to the development of ovarian serous carcinoma. Prostaglandins E mitochondrially encoded cytochrome c oxidase II Homo sapiens