Title : Comparison of rat and human cytochrome P450 (CYP) sources of N-alkylprotoporphyrin IX. Formation after interaction with porphyrinogenic xenobiotics: studies with cDNA-expressed single CYP enzymes.

Pub. Date : 2002 Nov

PMID : 12487729






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The porphyrinogenicity of certain xenobiotics is due to mechanism-based inactivation of selected cytochrome P450 (CYP) enzymes, with concurrent formation of N-alkylprotoporphyrins (N-alkylPPs), which disrupt control of haem biosynthesis. Heme cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 The porphyrinogenicity of certain xenobiotics is due to mechanism-based inactivation of selected cytochrome P450 (CYP) enzymes, with concurrent formation of N-alkylprotoporphyrins (N-alkylPPs), which disrupt control of haem biosynthesis. Heme cytochrome P450 family 4 subfamily F member 3 Homo sapiens