Title : Gender- and age-dependent changes in kidney androgen protein mRNA expression in a knockout mouse model for nephrolithiasis.

Pub. Date : 2002 Dec

PMID : 12486089






3 Functional Relationships(s)
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1 We previously observed a significant decrease in Kap mRNA expression in whole kidney tissue from male mice with adenine phosphoribosyltransferase (APRT) deficiency and 2,8-dihydroxyadenine (DHA) nephrolithiasis. 2,8-dihydroxyadenine kidney androgen regulated protein Mus musculus
2 We previously observed a significant decrease in Kap mRNA expression in whole kidney tissue from male mice with adenine phosphoribosyltransferase (APRT) deficiency and 2,8-dihydroxyadenine (DHA) nephrolithiasis. 2,8-dihydroxyadenine kidney androgen regulated protein Mus musculus
3 Kap expression is under multihormonal control, and hormonal changes in DHA-induced nephrolithiasis may account for the decreased Kap expression in APRT-deficient mice. 2,8-dihydroxyadenine kidney androgen regulated protein Mus musculus