Title : Changes in glutathione-related enzymes in tumor-bearing mice after cisplatin treatment.

Pub. Date : 2002

PMID : 12484546






2 Functional Relationships(s)
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1 In kidney, catalase activity decreased by 47-82% at all time points (24-96 h) of cisplatin treatment, while glutathione S-transferase activity decreased significantly (approximately 24%) mainly at 72 h of treatment. Cisplatin catalase Mus musculus
2 In Dalton lymphoma cells, the activities of glutathione S-transferase, glutathione peroxidase, and catalase decreased very distinctly (approximately 2-5, 2-5 and 5-11 times, respectively) at all time points, but glutathione reductase decreased significantly only at 72 h of cisplatin treatment. Cisplatin catalase Mus musculus