Title : Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure.

Pub. Date : 2003 Feb 21

PMID : 12482877






1 Functional Relationships(s)
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1 In Chinese hamster ovary (CHO) cells with moderate stable overexpression of SCD1, cholesterol efflux to apoA-I was inhibited by 73%, whereas phospholipid efflux and ABCA1 protein levels were unchanged. Phospholipids stearoyl-CoA desaturase Homo sapiens