Title : The V proteins of simian virus 5 and other paramyxoviruses inhibit induction of interferon-beta.

Pub. Date : 2002 Nov 10

PMID : 12482656






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In the absence of the viral V protein cysteine-rich C-terminal domain, IFN-beta mRNA is strongly induced and the transcription factors NF-kappaB and IRF-3 are activated significantly. Cysteine interferon beta 1 Homo sapiens
2 Blocking of the induction of IFN-beta by dsRNA requires the C-terminal cysteine-rich domain, a feature that is highly conserved among paramyxoviruses. Cysteine interferon beta 1 Homo sapiens