Title : Bcl-2 controls caspase activation following a p53-dependent cyclin D1-induced death signal.

Pub. Date : 2003 Apr 18

PMID : 12480939






1 Functional Relationships(s)
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1 MCF-7 and ZR-75 breast cancer cells infected with an adenovirus constitutively expressing high levels of cyclin D1 demonstrated widespread mitochondrial translocation of Bax and cytochrome c release that was approximately doubled after the addition of all-trans retinoic acid (RA) or Bcl-2 antisense oligonucleotide. Tretinoin cyclin D1 Homo sapiens