Pub. Date : 2003 Jan 1
PMID : 12478621
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The typical antipsychotic drug haloperidol has been shown to cause a decrease in the expression of brain-derived neurotrophic factor (BDNF), which plays an important role in neuronal cell survival, differentiation, and neuronal connectivity. | Haloperidol | brain-derived neurotrophic factor | Rattus norvegicus |
| 2 | The typical antipsychotic drug haloperidol has been shown to cause a decrease in the expression of brain-derived neurotrophic factor (BDNF), which plays an important role in neuronal cell survival, differentiation, and neuronal connectivity. | Haloperidol | brain-derived neurotrophic factor | Rattus norvegicus |
| 3 | Quantitative analysis revealed that the typical antipsychotic drug haloperidol (1 mg/kg) down-regulated BDNF mRNA expression in both CA1 (P < 0.05) and dentate gyrus (P < 0.01) regions compared with vehicle control. | Haloperidol | brain-derived neurotrophic factor | Rattus norvegicus |