Title : Regulation of isoprenoid/cholesterol biosynthesis in cells from mevalonate kinase-deficient patients.

Pub. Date : 2003 Feb 21

PMID : 12477733






1 Functional Relationships(s)
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1 Indeed, the isoprenylation of Ras and RhoA protein appeared normal in HIDS and MA fibroblasts under normal conditions but showed increased sensitivity toward inhibition of HMGR by simvastatin. Simvastatin high mobility group AT-hook 1 Homo sapiens