Pub. Date : 2002 Dec
PMID : 12475372
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In vivo administration of triiodothyronine (T(3)) or thyroxine (T(4)) significantly reduced pituitary and serum GH levels, as measured by homologous RIA. | Triiodothyronine | growth hormone 1 | Homo sapiens |
| 2 | Both T(3) and T(4) inhibited GH release in a concentration-dependent manner, producing up to 50% inhibition at 10 nM, with an ED(50) of <0.2 nM, within the range of their physiological circulating levels. | Triiodothyronine | growth hormone 1 | Homo sapiens |
| 3 | This demonstrated that the inhibition of T(3) on GH synthesis was mediated by a decrease in GH mRNA steady state levels. | Triiodothyronine | growth hormone 1 | Homo sapiens |
| 4 | This demonstrated that the inhibition of T(3) on GH synthesis was mediated by a decrease in GH mRNA steady state levels. | Triiodothyronine | growth hormone 1 | Homo sapiens |