Title : Gene therapy for prostate cancer by targeting poly(ADP-ribose) polymerase.

Pub. Date : 2002 Dec 1

PMID : 12460902






2 Functional Relationships(s)
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1 Furthermore, we found that PARP-DBD sensitized LNCaP cells to DNA-damaging agents, such as ionizing radiation and etoposide. Etoposide poly(ADP-ribose) polymerase 1 Homo sapiens
2 Androgen (R1881) -dependent stimulation of PARP-DBD expression resulted in a 2-fold growth inhibition in LNCaP cells as compared with controls, and an augmented apoptotic cell death in response to ionizing radiation or etoposide. Etoposide poly(ADP-ribose) polymerase 1 Homo sapiens